These Digestive Problems Signal Raised Parkinson’s Disease Risk
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- These Digestive Problems Signal Raised Parkinson’s Disease Risk
A new study has found there are four digestive problems that predict a higher risk of future Parkinson’s disease. These conditions are: dysphagia (trouble swallowing), gastroparesis, constipation and IBS (Irritable Bowel Syndrome) without diarrhea. This finding highlights the significant relationship between the gut and the brain. Disturbances in the health of the digestive tract can lead to poor brain health in the future. The study authors have said that “Experts have known for a very long time that constipation is a potential risk factor for Parkinson’s disease, so this study adds to the list of gastrointestinal conditions that could potentially be risk factors.”
Almost 90 thousand people in the United States are diagnosed with Parkinson’s disease each year. It is the second most common neurodegenerative disease after Alzheimer’s disease. The incidence of Parkinson’s disease rises with age and it is 1.5 times more common in men than women. It is a neurodegenerative disorder that affects the dopamine-producing neurons in a specific region of the brain called the substantia nigra.
Symptoms usually develop slowly over many years. The progression of symptoms is often a bit different from person to person due to the diversity of the disease. The following are the most common symptoms of Parkinson’s disease:
In addition to movement related symptoms, Parkinson’s disease can also cause non-motor symptoms such as depression, anxiety, cognitive impairment, apathy, hallucinations, disturbed sleep, constipation, orthostatic hypotension and loss of sense of smell.
Current treatments for Parkinson’s disease are not terribly effective; they are designed to replace dopamine and slow down the progression of the disease. Earlier studies have shown that an overgrowth of harmful gut bugs can increase the risk of Parkinson’s disease. This is because gut bugs communicate with the brain via nerves. Gut problems can also raise the risk of dementia and other neurodegenerative conditions.
Recently, studies have shown that oxidative stress in the brain actually plays a critical role in the development and progression of Parkinson’s disease. The oxidative stress lowers levels of glutathione, which is your body’s own antioxidant and designed to protect your brain from oxidative damage. Research conducted on brain cells shows that NAC (n-acetyl; cysteine) helps to reduce oxidative damage to neurons by helping to replenish the levels of glutathione.
The above statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease.
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